Cognitive performance related to HIV-1-infected monocytes.
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ABSTRACT:
SUBMITTER: Kusao I
PROVIDER: S-EPMC3335340 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Cognitive performance related to HIV-1-infected monocytes.
Kusao Ian I Shiramizu Bruce B Liang Chin-Yuan CY Grove John J Agsalda Melissa M Troelstrup David D Velasco Van-Nicholas VN Marshall Andrew A Whitenack Nicholas N Shikuma Cecilia C Valcour Victor V
The Journal of neuropsychiatry and clinical neurosciences 20120101 1
The effect that HIV type 1 (HIV) has on neurocognition is a dynamic process whereby peripheral events are likely involved in setting the stage for clinical findings. In spite of antiretroviral therapy (ART), patients continue to be at risk for HIV-associated neurocognitive disorders (HAND), which might be related to persistence of inflammation. In a yearly assessment of HIV DNA levels in activated monocytes, increased HIV DNA copies were found in patients with persistent HAND. Furthermore, activ ...[more]
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