Ontology highlight
ABSTRACT:
SUBMITTER: DeBaun MR
PROVIDER: S-EPMC3335377 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
DeBaun Michael R MR Sarnaik Sharada A SA Rodeghier Mark J MJ Minniti Caterina P CP Howard Thomas H TH Iyer Rathi V RV Inusa Baba B Telfer Paul T PT Kirby-Allen Melanie M Quinn Charles T CT Bernaudin Françoise F Airewele Gladstone G Woods Gerald M GM Panepinto Julie Ann JA Fuh Beng B Kwiatkowski Janet K JK King Allison A AA Rhodes Melissa M MM Thompson Alexis A AA Heiny Mark E ME Redding-Lallinger Rupa C RC Kirkham Fenella J FJ Sabio Hernan H Gonzalez Corina E CE Saccente Suzanne L SL Kalinyak Karen A KA Strouse John J JJ Fixler Jason M JM Gordon Mae O MO Miller J Phillip JP Noetzel Michael J MJ Ichord Rebecca N RN Casella James F JF
Blood 20111117 16
The most common form of neurologic injury in sickle cell anemia (SCA) is silent cerebral infarction (SCI). In the Silent Cerebral Infarct Multi-Center Clinical Trial, we sought to identify risk factors associated with SCI. In this cross-sectional study, we evaluated the clinical history and baseline laboratory values and performed magnetic resonance imaging of the brain in participants with SCA (HbSS or HbSβ° thalassemia) between the ages of 5 and 15 years with no history of overt stroke or seiz ...[more]