Ontology highlight
ABSTRACT:
SUBMITTER: Brodin JD
PROVIDER: S-EPMC3335442 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Brodin Jeffrey D JD Ambroggio X I XI Tang Chunyan C Parent Kristin N KN Baker Timothy S TS Tezcan F Akif FA
Nature chemistry 20120304 5
Proteins represent the most sophisticated building blocks available to an organism and to the laboratory chemist. Yet, in contrast to nearly all other types of molecular building blocks, the designed self-assembly of proteins has largely been inaccessible because of the chemical and structural heterogeneity of protein surfaces. To circumvent the challenge of programming extensive non-covalent interactions to control protein self-assembly, we have previously exploited the directionality and stren ...[more]