Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells.
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ABSTRACT:
SUBMITTER: Silver AC
PROVIDER: S-EPMC3336152 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
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Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells.
Silver Adam C AC Arjona Alvaro A Hughes Michael E ME Nitabach Michael N MN Fikrig Erol E
Brain, behavior, and immunity 20111013 3
In mammals, circadian and daily rhythms influence nearly all aspects of physiology, ranging from behavior to gene expression. Functional molecular clocks have been described in the murine spleen and splenic NK cells. The aim of our study was to investigate the existence of molecular clock mechanisms in other immune cells. Therefore, we measured the circadian changes in gene expression of clock genes (Per1, Per2, Bmal1, and Clock) and clock-controlled transcription factors (Rev-erbα and Dbp) in s ...[more]
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