Ontology highlight
ABSTRACT:
SUBMITTER: Chakraborty S
PROVIDER: S-EPMC3337693 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Chakraborty Sandipan S Chaudhuri Sudip S Pahari Biswapathik B Taylor Jasmine J Sengupta Pradeep K PK Sengupta Bidisha B
Journal of luminescence 20120601 6
Hesperitin, a ubiquitous bioactive flavonoid abundant in citrus fruits is known to possess antioxidant, anti-carcinogenic, hypolipidemic, vasoprotective and other important therapeutic properties. Here we have explored the interactions of hesperitin with normal human hemoglobin (HbA), using steady state and time resolved fluorescence spectroscopy, far UV circular dicroism (CD) spectroscopy, combined with molecular modeling computations. Specific interaction of the flavonoid with HbA is confirmed ...[more]