Ontology highlight
ABSTRACT:
SUBMITTER: Wang F
PROVIDER: S-EPMC3338343 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Wang Fay F Flanagan John J Su Nan N Wang Li-Chong LC Bui Son S Nielson Allissa A Wu Xingyong X Vo Hong-Thuy HT Ma Xiao-Jun XJ Luo Yuling Y
The Journal of molecular diagnostics : JMD 20120101 1
In situ analysis of biomarkers is highly desirable in molecular pathology because it allows the examination of biomarker status within the histopathological context of clinical specimens. Immunohistochemistry and DNA in situ hybridization (ISH) are widely used in clinical settings to assess protein and DNA biomarkers, respectively, but clinical use of in situ RNA analysis is rare. This disparity is especially notable when considering the abundance of RNA biomarkers discovered through whole-genom ...[more]