Ontology highlight
ABSTRACT:
SUBMITTER: Wong KA
PROVIDER: S-EPMC3338775 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Wong Katy A KA Wilson Jessica J Russo Angela A Wang Li L Okur Mustafa Nazir MN Wang Xuerong X Martin Negin P NP Scappini Erica E Carnegie Graeme K GK O'Bryan John P JP
PloS one 20120427 4
Members of the intersectin (ITSN) family of scaffold proteins consist of multiple modular domains, each with distinct ligand preferences. Although ITSNs were initially implicated in the regulation of endocytosis, subsequent studies have revealed a more complex role for these scaffold proteins in regulation of additional biochemical pathways. In this study, we performed a high throughput yeast two-hybrid screen to identify additional pathways regulated by these scaffolds. Although several known I ...[more]