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Developmental risk I: depression and the developing brain.


ABSTRACT: This article discusses recent findings on the neurobiology of pediatric depression as well as the interplay between genetic and environmental factors in determining the risk for the disorder. Utilizing data from both animal and human studies, the authors focus on the evolving understanding of the developmental neurobiology of emotional regulation, cognitive function and social behavior as it applies to the risk and clinical course of depression. Treatment implications and directions for future research are also discussed.

SUBMITTER: Weir JM 

PROVIDER: S-EPMC3338920 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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Developmental risk I: depression and the developing brain.

Weir John M JM   Zakama Arthurine A   Rao Uma U  

Child and adolescent psychiatric clinics of North America 20120217 2


This article discusses recent findings on the neurobiology of pediatric depression as well as the interplay between genetic and environmental factors in determining the risk for the disorder. Utilizing data from both animal and human studies, the authors focus on the evolving understanding of the developmental neurobiology of emotional regulation, cognitive function and social behavior as it applies to the risk and clinical course of depression. Treatment implications and directions for future r  ...[more]

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2016-11-01 | GSE88890 | GEO