Ontology highlight
ABSTRACT:
SUBMITTER: Sen YH
PROVIDER: S-EPMC3341097 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Sen Yi-Heng YH Jain Tarun T Aguilar Carlos A CA Karnik Rohit R
Lab on a chip 20120202 6
Nanofluidic sensing elements have been the focus of recent experiments for numerous applications ranging from nucleic acid fragment sizing to single-molecule DNA sequencing. These applications critically rely on high measurement fidelity, and methods to increase resolution are required. Herein, we describe fabrication and testing of a nanochannel device that enhances measurement resolution by performing multiple measurements (>100) on single DNA molecules. The enhanced measurement resolution ena ...[more]