Glaucoma 2.0: neuroprotection, neuroregeneration, neuroenhancement.
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ABSTRACT:
SUBMITTER: Chang EE
PROVIDER: S-EPMC3343191 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Publications
Glaucoma 2.0: neuroprotection, neuroregeneration, neuroenhancement.
Chang Elma E EE Goldberg Jeffrey L JL
Ophthalmology 20120218 5
Glaucoma is a progressive neurodegenerative disease of retinal ganglion cells (RGCs) associated with characteristic axon degeneration in the optic nerve. Clinically, our only method of slowing glaucomatous loss of vision is to reduce intraocular pressure (IOP), but lowering IOP is only partially effective and does not address the underlying susceptibility of RGCs to degeneration. We review the recent steps forward in our understanding of the pathophysiology of glaucoma and discuss how this under ...[more]
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