Basal breast cancer: a complex and deadly molecular subtype.
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ABSTRACT:
SUBMITTER: Bertucci F
PROVIDER: S-EPMC3343384 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
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Basal breast cancer: a complex and deadly molecular subtype.
Bertucci F F Finetti P P Birnbaum D D
Current molecular medicine 20120101 1
During the last decade, gene expression profiling of breast cancer has revealed the existence of five molecular subtypes and allowed the establishment of a new classification. The basal subtype, which represents 15-25% of cases, is characterized by an expression profile similar to that of myoepithelial normal mammary cells. Basal tumors are frequently assimilated to triple-negative (TN) breast cancers. They display epidemiological and clinico-pathological features distinct from other subtypes. T ...[more]
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