Ontology highlight
ABSTRACT:
SUBMITTER: Chang HH
PROVIDER: S-EPMC3343740 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Chang Hsun-Hsien HH McGeachie Michael M
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 20110101
A long-term goal of biomedical research is to decipher how genetic processes influence disease formation. Ubiquitous and advancing microarray technology can measure millions of DNA structural variants (single-nucleotide polymorphisms, or SNPs) and thousands of gene transcripts (RNA expression microarrays) in cells. Both of these information modalities can be brought to bear on disease etiology. This paper develops a Bayesian network-based approach to integrate SNP and expression microarray data. ...[more]