Ontology highlight
ABSTRACT:
SUBMITTER: Gorse GJ
PROVIDER: S-EPMC3346329 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Gorse Geoffrey J GJ Newman Mark J MJ deCamp Allan A Hay Christine Mhorag CM De Rosa Stephen C SC Noonan Elizabeth E Livingston Brian D BD Fuchs Jonathan D JD Kalams Spyros A SA Cassis-Ghavami Farah L FL
Clinical and vaccine immunology : CVI 20120307 5
We evaluated a DNA plasmid-vectored vaccine and a recombinant modified vaccinia virus Ankara vaccine (MVA-mBN32), each encoding cytotoxic and helper T-lymphocyte epitopes of human immunodeficiency virus type 1 (HIV-1) in a randomized, double-blinded, placebo-controlled trial in 36 HIV-1-uninfected adults using a heterologous prime-boost schedule. HIV-1-specific cellular immune responses, measured as interleukin-2 and/or gamma interferon production, were induced in 1 (4%) of 28 subjects after the ...[more]