Ontology highlight
ABSTRACT:
SUBMITTER: Baron F
PROVIDER: S-EPMC3347667 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Baron Frédéric F Suciu Stefan S Amadori Sergio S Muus Petra P Zwierzina Heinz H Denzlinger Claudio C Delforge Michel M Thyss Antoine A Selleslag Dominik D Indrak Karel K Ossenkoppele Gert G de Witte Theo T
Haematologica 20111118 4
Tumor-necrosis factor alpha activity has been correlated to ineffective erythropoiesis in lower risk myelodysplastic syndromes. Infliximab (Remicade(®)) is an anti-tumor necrosis factor alpha chimeric antibody that is used in the treatment of patients with rheumatoid arthritis or Crohn's disease. Forty-six patients with myelodysplastic syndromes and a relatively low risk of developing acute leukemia were included in a randomized phase II study assessing the therapeutic activity of two dosages of ...[more]