Ontology highlight
ABSTRACT:
SUBMITTER: Lorenzi T
PROVIDER: S-EPMC3350501 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Lorenzi Teresa T Turi Angelo A Lorenzi Maria M Paolinelli Francesca F Mancioli Francesca F La Sala Lucia L Morroni Manrico M Ciarmela Pasquapina P Mantovani Angelo A Tranquilli Andrea Luigi AL Castellucci Mario M Marzioni Daniela D
PloS one 20120511 5
<h4>Context and objective</h4>The etiology of miscarriage is often multifactorial. One major cause, immunological rejection of the fetus, has not been clearly elucidated. Our aim was to establish whether the semaphorin CD100, its natural receptor CD72, and the glycoprotein CD45, implicated in immune mechanisms, are involved in pregnancy loss by examining their placental expression with real-time PCR, immunohistochemistry and western blotting techniques.<h4>Patients</h4>Placenta tissue from 72 Ca ...[more]