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Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others.


ABSTRACT: Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine.

SUBMITTER: Kitzmiller JP 

PROVIDER: S-EPMC3351041 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

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Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others.

Kitzmiller Joseph P JP   Groen David K DK   Phelps Mitch A MA   Sadee Wolfgang W  

Cleveland Clinic journal of medicine 20110401 4


Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine. ...[more]

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