Ontology highlight
ABSTRACT:
SUBMITTER: Kuo HC
PROVIDER: S-EPMC3354684 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Kuo Ho-Chang HC Chao Mei-Chyn MC Hsu Yu-Wen YW Lin Ying-Chi YC Huang Ying-Hsien YH Yu Hong-Ren HR Hou Ming-Feng MF Liang Chi-Di CD Yang Kuender D KD Chang Wei-Chiao WC Wang Chih-Lu CL
TheScientificWorldJournal 20120502
<h4>Background</h4>Kawasaki disease (KD) is characterized by systemic vasculitis of unknown etiology. Our previous studies showed expression of CD40 ligand on CD4+ T cells correlated to the coronary artery lesion (CAL) and disease progress in KD. Other studies from Japan suggested the role of CD40L in the pathogenesis of CAL, and this might help explain the excessive number of males affected with KD but cannot be reproduced by Taiwanese population. This study was conducted to investigate the CD4 ...[more]