Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer.
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ABSTRACT:
SUBMITTER: Shimma S
PROVIDER: S-EPMC3356408 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
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Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer.
Shimma Shuichi S Kubo Ayumi A Satoh Takaya T Toyoda Michisato M
PloS one 20120518 5
Direct tissue analysis using a novel tandem time-of-flight (TOF-TOF) mass spectrometer is described. This system consists of a matrix-assisted laser desorption/ionization ion source, a spiral ion trajectory TOF mass spectrometer "SpiralTOF (STOF)", a collision cell, and an offset parabolic reflectron (RTOF). The features of this system are high precursor ion selectivity due to a 17-m flight path length in STOF and elimination of post-source decay (PSD) ions. The acceleration energy is 20 keV, so ...[more]
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