Schizosaccharomyces pombe homologs of the Saccharomyces cerevisiae mitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis.
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ABSTRACT:
SUBMITTER: Kuhl I
PROVIDER: S-EPMC3361529 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
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Schizosaccharomyces pombe homologs of the Saccharomyces cerevisiae mitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis.
Kühl Inge I Fox Thomas D TD Bonnefoy Nathalie N Bonnefoy Nathalie N
Mitochondrion 20120210 3
Complexes III and IV of the mitochondrial respiratory chain contain a few key subunits encoded by the mitochondrial genome. In Saccharomyces cerevisiae, fifteen mRNA-specific translational activators control mitochondrial translation, of which five are conserved in Schizosaccharomyces pombe. These include homologs of Cbp3, Cbp6 and Mss51 that participate in translation and the post-translational steps leading to the assembly of respiratory complexes III and IV. In this study we show that in cont ...[more]
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