Ontology highlight
ABSTRACT:
SUBMITTER: Sahin AO
PROVIDER: S-EPMC3364136 | biostudies-literature | 2012 Jan-Feb
REPOSITORIES: biostudies-literature
Sahin Aysegul Ocal AO Buitenhuis Miranda M
Cell adhesion & migration 20120101 1
Hematopoietic stem cell transplantation is the most powerful treatment modality for a large number of hematopoietic malignancies, including leukemia. Successful hematopoietic recovery after transplantation depends on homing of hematopoietic stem cells to the bone marrow and subsequent lodging of those cells in specific niches in the bone marrow. Migration of hematopoietic stem cells to the bone marrow is a highly regulated process that requires correct regulation of the expression and activity o ...[more]