Ontology highlight
ABSTRACT:
SUBMITTER: Gebert M
PROVIDER: S-EPMC3365495 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
The Journal of cell biology 20120521 5
Many mitochondrial proteins are synthesized with N-terminal presequences in the cytosol. The presequence translocase of the inner mitochondrial membrane (TIM23) translocates preproteins into and across the membrane and associates with the matrix-localized import motor. The TIM23 complex consists of three core components and Tim21, which interacts with the translocase of the outer membrane (TOM) and the respiratory chain. We have identified a new subunit of the TIM23 complex, the inner membrane p ...[more]