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Regulation of polyphosphate kinase production by antisense RNA in Pseudomonas fluorescens Pf0-1.


ABSTRACT: Pseudomonas spp. adapt rapidly to environmental fluctuations. Loss or overproduction of polyphosphate reduces the fitness of Pseudomonas fluorescens Pf0-1, indicating the importance of the fine-tuning of polyphosphate production. An antisense RNA was investigated and shown to regulate the polyphosphate kinase gene (ppk) by a posttranscriptional mechanism reducing ppk transcript abundance.

SUBMITTER: Silby MW 

PROVIDER: S-EPMC3370510 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Regulation of polyphosphate kinase production by antisense RNA in Pseudomonas fluorescens Pf0-1.

Silby Mark W MW   Nicoll Julie S JS   Levy Stuart B SB  

Applied and environmental microbiology 20120406 12


Pseudomonas spp. adapt rapidly to environmental fluctuations. Loss or overproduction of polyphosphate reduces the fitness of Pseudomonas fluorescens Pf0-1, indicating the importance of the fine-tuning of polyphosphate production. An antisense RNA was investigated and shown to regulate the polyphosphate kinase gene (ppk) by a posttranscriptional mechanism reducing ppk transcript abundance. ...[more]

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