Diversity of integron- and culture-associated antibiotic resistance genes in freshwater floc.

ABSTRACT: Clinically important antibiotic resistance genes were detected in culturable bacteria and class 1 integron gene cassettes recovered from suspended floc, a significant aquatic repository for microorganisms and trace elements, across freshwater systems variably impacted by anthropogenic activities. Antibiotic resistance gene cassettes in floc total community DNA differed appreciably in number and type from genes detected in bacteria cultured from floc. The number of floc antibiotic resistance gene cassette types detected across sites was positively correlated with total (the sum of Ag, As, Cu, and Pb) trace element concentrations in aqueous solution and in a component of floc readily accessible to bacteria. In particular, concentrations of Cu and Pb in the floc component were positively corr

SUBMITTER: Drudge CN 

PROVIDER: S-EPMC3370513 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature