Ontology highlight
ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC3370654 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Liu Liping L Lai Chao-Qiang CQ Nie Lin L Ordovas Jose J Band Michael M Moser Leta L Meydani Mohsen M
Molecular nutrition & food research 20081001 10
Human and animal studies have shown that green tea consumption is associated with a reduced risk of some cancers. This has been attributed to its polyphenol components, in particular (-)-epigallocatechin gallate (EGCG). In addition to be a cancer chemopreventive agent, EGCG inhibits angiogenesis, thus reducing tumor growth and metastasis. We tested EGCG modulation on the gene expression profile of endothelial cells stimulated by VEGF using Affymetrix microarrays. A total of 421 genes were up-reg ...[more]