Ontology highlight
ABSTRACT:
SUBMITTER: Penman GA
PROVIDER: S-EPMC3370916 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Penman George A GA Lockhart Deborah E A DE Ferenbach Andrew A van Aalten Daan M F DM
Acta crystallographica. Section F, Structural biology and crystallization communications 20120523 Pt 6
Aspergillus fumigatus UDP-galactopyranose mutase (AfUGM) is a potential drug target involved in the synthesis of the cell wall of this fungal pathogen. AfUGM was recombinantly produced in Escherichia coli, purified and crystallized by the sitting-drop method, producing orthorhombic crystals that diffracted to a resolution of 3.25 Å. The crystals contained four molecules per asymmetric unit and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 127.72, b = 134.30, c = 173.84 Å. ...[more]