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Tachyon search speeds up retrieval of similar sequences by several orders of magnitude.

ABSTRACT:

Unlabelled

The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic.

Availability and implementation

The tool is publicly accessible as a webserver at http://tachyon.bii.a-star.edu.sg and can also be accessed programmatically through SOAP.

SUBMITTER: Tan J

PROVIDER: S-EPMC3371831 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Tachyon search speeds up retrieval of similar sequences by several orders of magnitude.

Tan Joshua J Kuchibhatla Durga D Sirota Fernanda L FL Sherman Westley A WA Gattermayer Tobias T Kwoh Chia Yee CY Eisenhaber Frank F Schneider Georg G Maurer-Stroh Sebastian S

Bioinformatics (Oxford, England) 20120423 12

<h4>Unlabelled</h4>The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic.<h4>Availability and implementation</h4>The tool is publicly accessible as a webserver at http://tachyon.bii.a-star.edu.sg and can also be acc ...[more]

PMID: 22531216

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