Mus spicilegus endogenous retrovirus HEMV uses murine sodium-dependent myo-inositol transporter 1 as a receptor.
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ABSTRACT:
SUBMITTER: Tipper CH
PROVIDER: S-EPMC3372175 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
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Mus spicilegus endogenous retrovirus HEMV uses murine sodium-dependent myo-inositol transporter 1 as a receptor.
Tipper Christopher H CH Cingöz Oya O Coffin John M JM
Journal of virology 20120328 11
We sought to determine the relationship between two recent additions to the murine leukemia virus (MLV) ecotropic subgroup: Mus cervicolor isolate M813 and Mus spicilegus endogenous retrovirus HEMV. Though divergent in sequence, the two viruses share an Env protein with similarly curtailed VRA and VRB regions, and infection by both is restricted to mouse cells. HEMV and M813 displayed reciprocal receptor interference, suggesting that they share a receptor. Expression of the M813 receptor murine ...[more]
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