Ontology highlight
ABSTRACT:
SUBMITTER: Krause JC
PROVIDER: S-EPMC3372199 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Krause Jens C JC Tsibane Tshidi T Tumpey Terrence M TM Huffman Chelsey J CJ Albrecht Randy R Blum David L DL Ramos Irene I Fernandez-Sesma Ana A Edwards Kathryn M KM García-Sastre Adolfo A Basler Christopher F CF Crowe James E JE
Journal of virology 20120328 11
Investigation of the human antibody response to the 1957 pandemic H2N2 influenza A virus has been largely limited to serologic studies. We generated five influenza virus hemagglutinin (HA)-reactive human monoclonal antibodies (MAbs) by hybridoma technology from the peripheral blood of healthy donors who were born between 1950 and 1968. Two MAbs reacted with the pandemic H2N2 virus, two recognized the pandemic H3N2 virus, and remarkably, one reacted with both the pandemic H2N2 and H3N2 viruses. E ...[more]