Ontology highlight
ABSTRACT:
SUBMITTER: Lane AL
PROVIDER: S-EPMC3374858 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Lane Amy L AL Stout Elizabeth P EP Hay Mark E ME Prusak Anne C AC Hardcastle Kenneth K Fairchild Craig R CR Franzblau Scott G SG Le Roch Karine K Prudhomme Jacques J Aalbersberg William W Kubanek Julia J
The Journal of organic chemistry 20070823 19
Callophycoic acids A-H (1-8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene-benzoic acids and diterpene-phenols in macroalgae. Compounds 1-10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides pr ...[more]