Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

ABSTRACT: Callophycoic acids A-H (1-8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene-benzoic acids and diterpene-phenols in macroalgae. Compounds 1-10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.

SUBMITTER: Lane AL 

PROVIDER: S-EPMC3374858 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature