Ontology highlight
ABSTRACT:
SUBMITTER: Bukoreshtliev NV
PROVIDER: S-EPMC3375158 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Bukoreshtliev Nickolay Vassilev NV Hodneland Erlend E Eichler Tilo Wolf TW Eifart Patricia P Rustom Amin A Gerdes Hans-Hermann HH
International journal of cell biology 20120606
The biogenesis, maturation, and exocytosis of secretory granules in interphase cells have been well documented, whereas the distribution and exocytosis of these hormone-storing organelles during cell division have received little attention. By combining ultrastructural analyses and time-lapse microscopy, we here show that, in dividing PC12 cells, the prominent peripheral localization of secretory granules is retained during prophase but clearly reduced during prometaphase, ending up with only fe ...[more]