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Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study.


ABSTRACT: We reexamined the finding of an inverse relationship between values of nasopharyngeal lactate dehydrogenase, a marker of the innate immune response, and bronchiolitis severity. In a prospective, multicenter study of 258 children, we found in a multivariable model that higher nasopharyngeal lactate dehydrogenase values in young children with bronchiolitis were independently associated with a decreased risk of hospitalization.

SUBMITTER: Mansbach JM 

PROVIDER: S-EPMC3375381 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature

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Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study.

Mansbach Jonathan M JM   Piedra Pedro A PA   Laham Federico R FR   McAdam Alexander J AJ   Clark Sunday S   Sullivan Ashley F AF   Camargo Carlos A CA  

The Pediatric infectious disease journal 20120701 7


We reexamined the finding of an inverse relationship between values of nasopharyngeal lactate dehydrogenase, a marker of the innate immune response, and bronchiolitis severity. In a prospective, multicenter study of 258 children, we found in a multivariable model that higher nasopharyngeal lactate dehydrogenase values in young children with bronchiolitis were independently associated with a decreased risk of hospitalization. ...[more]

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