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Neutrophil CD64 as a diagnostic marker in neonatal sepsis.


ABSTRACT: We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.

SUBMITTER: Streimish I 

PROVIDER: S-EPMC3375383 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature

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Neutrophil CD64 as a diagnostic marker in neonatal sepsis.

Streimish Iris I   Bizzarro Matthew M   Northrup Veronika V   Wang Chao C   Renna Sara S   Koval Nancy N   Li Fang-Yong FY   Ehrenkranz Richard R   Rinder Henry M HM   Bhandari Vineet V  

The Pediatric infectious disease journal 20120701 7


We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis. ...[more]

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