Ontology highlight
ABSTRACT:
SUBMITTER: Pan C
PROVIDER: S-EPMC3376093 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Pan Chuanyong C Chen Huan H Wang Lianghua L Yang Shengsheng S Fu Hailong H Zheng Yongxia Y Miao Mingyong M Jiao Binghua B
PloS one 20120615 6
Liver regeneration (LR) after partial hepatectomy (PH) involves the proliferation and apoptosis of hepatocytes, and microRNAs have been shown to post-transcriptionally regulate genes involved in the regulation of these processes. To explore the role of miR-127 during LR, the expression patterns of miR-127 and its related proteins were investigated. MiR-127 was introduced into a rat liver cell line to examine its effects on the potential target genes Bcl6 and Setd8, and functional studies were un ...[more]