Unknown

Dataset Information

0

Selective fluorescence detection of cysteine and N-terminal cysteine peptide residues.

ABSTRACT: A new fluorogenic fluorescein derivative containing an alpha,beta-unsaturated aldehyde moiety produces a selective fluorescent signal enhancement in the presence of cysteine or peptides containing N-terminal cysteine residues. The mechanism is based on synergistic covalent and supramolecular interactions.

SUBMITTER: Lim S 

PROVIDER: S-EPMC3376164 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Selective fluorescence detection of cysteine and N-terminal cysteine peptide residues.

Lim Soojin S   Escobedo Jorge O JO   Lowry Mark M   Xu Xiangyang X   Strongin Robert R  

Chemical communications (Cambridge, England) 20100708 31

A new fluorogenic fluorescein derivative containing an alpha,beta-unsaturated aldehyde moiety produces a selective fluorescent signal enhancement in the presence of cysteine or peptides containing N-terminal cysteine residues. The mechanism is based on synergistic covalent and supramolecular interactions. ...[more]

Similar Datasets

Transcriptomics Covalent targeting of remote cysteine residues for the development of selective CDK12/13 inhibitors
2015-08-13 | E-GEOD-72031 | biostudies-arrayexpress
Unknown A Selective Cucurbit[8]uril-Peptide Beacon Ensemble for the Ratiometric Fluorescence Detection of Peptides.
| S-EPMC6856807 | biostudies-literature
Unknown Selective and Reversible Photochemical Derivatization of Cysteine Residues in Peptides and Proteins.
| S-EPMC3994131 | biostudies-literature
Unknown Goat immunolobulin G. Peptide chains and terminal residues.
| S-EPMC1185115 | biostudies-other
Unknown Rapid and selective modification of phosphoserine residues catalysed by Ba2+ ions for their detection during peptide microsequencing.
| S-EPMC1130629 | biostudies-other
Unknown Amino-terminal cysteine residues differentially influence RGS4 protein plasma membrane targeting, intracellular trafficking, and function.
| S-EPMC3436580 | biostudies-literature
Unknown Fluorescence of peptide N-terminal 2-oxoacyl and quinoxaline derivatives.
| S-EPMC1133106 | biostudies-other
Unknown Selective loss of cysteine residues and disulphide bonds in a potato proteinase inhibitor II family.
| S-EPMC3073943 | biostudies-literature
Unknown Efficient Chemical Protein Synthesis using Fmoc-Masked N-Terminal Cysteine in Peptide Thioester Segments.
| S-EPMC7891605 | biostudies-literature
Unknown Discovery of a 29-Amino-Acid Reactive Abiotic Peptide for Selective Cysteine Arylation.
| S-EPMC5856623 | biostudies-literature