Ontology highlight
ABSTRACT:
SUBMITTER: Dominguez-Medina S
PROVIDER: S-EPMC3378771 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Dominguez-Medina Sergio S McDonough Steven S Swanglap Pattanawit P Landes Christy F CF Link Stephan S
Langmuir : the ACS journal of surfaces and colloids 20120502 24
We present in situ observations of adsorption of bovine serum albumin (BSA) on citrate-stabilized gold nanospheres. We implemented scattering correlation spectroscopy as a tool to quantify changes in the nanoparticle brownian motion resulting from BSA adsorption onto the nanoparticle surface. Protein binding was observed as an increase in the nanoparticle hydrodynamic radius. Our results indicate the formation of a protein monolayer at similar albumin concentrations as those found in human blood ...[more]