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1-Ethyl-4-[1-(1-phenyl-ethyl-idene)hydrazin-2-yl-idene]-3,4-dihydro-1H-2?(6),1-benzothia-zine-2,2-dione.

ABSTRACT: In the title compound, C(18)H(19)N(3)O(2)S, the thia-zine ring adopts an envelope conformation, with the S atom displaced by 0.732?(1)?Å from the other atoms of the ring. The phenyl ring is oriented at a dihedral angle of 79.33?(7)° with respect to the fused benzene ring. The conformations about the two double bonds in the R(2)C=N-N=C(CH(3))Ar grouping are Z and E, respectively. In the crystal, inversion dimers linked by pairs of C-H?O inter-actions generate R(2) (2)(8) and R(2) (2)(12) loops, as parts of infinite chains along the a-axis direction.

SUBMITTER: Shafiq M

PROVIDER: S-EPMC3379482 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Comparison of SARS-CoV-2 Omicron nucleic acid test for COVID-19 infection with real-time RT-PCR using different nasopharyngeal swabs

Li Sujuan S Zhang Yuanhang Y Tong Peng cheng Pc Yang Wei W

20230624

<h4>Background: </h4> A new one SARS-CoV-2 Variant of Concern (VoC), Omicron, was born in a world weary of COVID-19, which anger and frustration with the pandemic was widespread, with wide-ranging negative impacts on health, social and economic well-being. The Omicron variant, which main types was BA5.2and BF.7 in China, in December 2022 to January 2023 leaded to off-target of the S and N genes, and the kits used were not adequately and independently evaluated when these agents are studied and d ...[more]

PMID: PPR679709

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Project description:In the title compound, C(16)H(13)ClFN(3)O(2)S, the dihedral angle between the benzene rings is 4.47?(3)°. The conformation of the thia-zine ring is a half-chair and the Cl atom is in an axial orientation. In the crystal, mol-ecules are linked by C-H?F inter-actions, generating C(12) chains propagating in [011]. Aromatic ?-? stacking inter-actions [centroid-centroid separations = 3.753?(2) and 3.758?(2)?Å] also occur.

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3-Chloro-4-[2-(4-chloro-benzyl-idene)hydrazinyl-idene]-1-methyl-3,4-dihydro-1H-2?(6),1-benzothia-zine-2,2-dione.

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