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Leptin and the central nervous system control of glucose metabolism.

ABSTRACT: The regulation of body fat stores and blood glucose levels is critical for survival. This review highlights growing evidence that leptin action in the central nervous system plays a key role in both processes. Investigation into underlying mechanisms has begun to clarify the physiological role of leptin in the control of glucose metabolism and raises interesting new possibilities for the treatment of diabetes and related disorders.

SUBMITTER: Morton GJ

PROVIDER: S-EPMC3379883 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

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Leptin and the central nervous system control of glucose metabolism.

Morton Gregory J GJ Schwartz Michael W MW

Physiological reviews 20110401 2

The regulation of body fat stores and blood glucose levels is critical for survival. This review highlights growing evidence that leptin action in the central nervous system plays a key role in both processes. Investigation into underlying mechanisms has begun to clarify the physiological role of leptin in the control of glucose metabolism and raises interesting new possibilities for the treatment of diabetes and related disorders. ...[more]

PMID: 21527729

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