Ontology highlight
ABSTRACT:
SUBMITTER: Bethune MT
PROVIDER: S-EPMC3382113 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Bethune Michael T MT Khosla Chaitan C
Methods in enzymology 20120101
Celiac sprue is an inflammatory disease of the small intestine caused by dietary gluten and treated by adherence to a life-long gluten-free diet. The recent identification of immunodominant gluten peptides, the discovery of their cogent properties, and the elucidation of the mechanisms by which they engender immunopathology in genetically susceptible individuals have advanced our understanding of the molecular pathogenesis of this complex disease, enabling the rational design of new therapeutic ...[more]