Ontology highlight
ABSTRACT:
SUBMITTER: Niwa T
PROVIDER: S-EPMC3384135 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Niwa Tatsuya T Kanamori Takashi T Ueda Takuya T Taguchi Hideki H
Proceedings of the National Academy of Sciences of the United States of America 20120521 23
Protein folding is often hampered by protein aggregation, which can be prevented by a variety of chaperones in the cell. A dataset that evaluates which chaperones are effective for aggregation-prone proteins would provide an invaluable resource not only for understanding the roles of chaperones, but also for broader applications in protein science and engineering. Therefore, we comprehensively evaluated the effects of the major Escherichia coli chaperones, trigger factor, DnaK/DnaJ/GrpE, and Gro ...[more]