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Predictors of outcomes in the treatment of urge urinary incontinence in women.


ABSTRACT: Women with urge predominant urinary incontinence received active intervention (drug therapy alone or combined with behavioral therapy) for 10 weeks, then stopped all therapy and were followed for 6 months more. In this planned secondary analysis, we aimed to identify predictors of therapeutic success at 10 weeks (> or =70% reduction in incontinence) and of ability to discontinue treatment and sustain improvements 6 months later.Using data from 307 women, we performed logistic regression to identify predictors for outcomes described above.After controlling for group, only younger age was associated with short-term success (OR 0.8, 95% CI 0.66, 0.96). At 6 months, controlling for group and short-term outcome, only greater anterior vaginal wall prolapse was associated with successful discontinuation (POP-Q point Aa; OR 1.33, 95% CI 1.03, 1.7).These findings are not of sufficient strength to justify withholding conservative therapies but might be used to promote realistic expectations when counseling patients.

SUBMITTER: Richter HE 

PROVIDER: S-EPMC3384992 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature

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Predictors of outcomes in the treatment of urge urinary incontinence in women.

Richter Holly E HE   Burgio Kathryn L KL   Chai Toby C TC   Kraus Stephen R SR   Xu Yan Y   Nyberg Lee L   Brubaker Linda L  

International urogynecology journal and pelvic floor dysfunction 20090130 5


<h4>Introduction and hypothesis</h4>Women with urge predominant urinary incontinence received active intervention (drug therapy alone or combined with behavioral therapy) for 10 weeks, then stopped all therapy and were followed for 6 months more. In this planned secondary analysis, we aimed to identify predictors of therapeutic success at 10 weeks (> or =70% reduction in incontinence) and of ability to discontinue treatment and sustain improvements 6 months later.<h4>Methods</h4>Using data from  ...[more]

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