Genome-wide association study of porcine hematological parameters in a Large White × Minzhu F2 resource population.

ABSTRACT: Hematological traits, which are important indicators of immune function in animals, have been commonly examined as biomarkers of disease and disease severity in humans and animals. Genome-wide significant quantitative trait loci (QTLs) provide important information for use in breeding programs of animals such as pigs. QTLs for hematological parameters (hematological traits) have been detected in pig chromosomes, although these are often mapped by linkage analysis to large intervals making identification of the underlying mutation problematic. Single nucleotide polymorphisms (SNPs) are the common form of genetic variation among individuals and are thought to account for the majority of inherited traits. In this study, a genome-wide association study (GWAS) was performed to detect regions of

SUBMITTER: Luo W 

PROVIDER: S-EPMC3385009 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature