Ontology highlight
ABSTRACT:
SUBMITTER: Khazaie K
PROVIDER: S-EPMC3387103 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Khazaie Khashayarsha K Zadeh Mojgan M Khan Mohammad W MW Bere Praveen P Gounari Fotini F Dennis Kirsten K Blatner Nichole R NR Owen Jennifer L JL Klaenhammer Todd R TR Mohamadzadeh Mansour M
Proceedings of the National Academy of Sciences of the United States of America 20120611 26
An imbalance of commensal bacteria and their gene products underlies mucosal and, in particular, gastrointestinal inflammation and a predisposition to cancer. Lactobacillus species have received considerable attention as examples of beneficial microbiota. We have reported previously that deletion of the phosphoglycerol transferase gene that is responsible for lipoteichoic acid (LTA) biosynthesis in Lactobacillus acidophilus (NCK2025) rendered this bacterium able to significantly protect mice aga ...[more]