Ontology highlight
ABSTRACT:
SUBMITTER: Rouaud P
PROVIDER: S-EPMC3388189 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
Oncotarget 20120501 5
Mantle cell lymphoma (MCL) is a malignant lymphoproliferative B-cell disorder that does not occur spontaneously in mice but experimental mice model have been developed. Recently two different mice models prone to develop MCL-like lymphomas were generated: c-myc-3'RR/Cdk4(R24C) mice and c-myc-3'RR/p53+/- mice. Comparison of their gene expression profiles does not highlight specific differences other than those in relation with their specific mutational status (i.e., Cdk4(R24C) mutation or p53 mut ...[more]