Ontology highlight
ABSTRACT:
SUBMITTER: Terwilliger TC
PROVIDER: S-EPMC3388814 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Terwilliger Thomas C TC Read Randy J RJ Adams Paul D PD Brunger Axel T AT Afonine Pavel V PV Grosse-Kunstleve Ralf W RW Hung Li-Wei LW
Acta crystallographica. Section D, Biological crystallography 20120619 Pt 7
An approach is presented for addressing the challenge of model rebuilding after molecular replacement in cases where the placed template is very different from the structure to be determined. The approach takes advantage of the observation that a template and target structure may have local structures that can be superimposed much more closely than can their complete structures. A density-guided procedure for deformation of a properly placed template is introduced. A shift in the coordinates of ...[more]