Ontology highlight
ABSTRACT:
SUBMITTER: Gao Y
PROVIDER: S-EPMC3389024 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Gao Yanxiang Y Feng Juan J Ma Kongyang K Zhou Zhou Z Zhu Yi Y Xu Qingbo Q Wang Xian X
PloS one 20120703 7
Epoxyeicosatrienoic acids (EETs), synthesized from arachidonic acid by cytochrome P450 epoxygenases, are converted to dihydroxyeicosatrienoic acids by soluble epoxide hydrolase. EETs exert anti-inflammatory effects. However, the effect of EETs on humoral immunity is poorly understood. The present study is to investigate the potential role of EETs on B cell function and mechanisms. We examined the role of EETs on antibody production of splenic B cells from C57BL/6 and apolipoprotein E-deficient ( ...[more]