Ontology highlight
ABSTRACT:
SUBMITTER: Leggat JA
PROVIDER: S-EPMC3389734 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Leggat Jamie A JA Gibbons Deena L DL Haque Syeda F Y SF Smith Adrian L AL Wells James W JW Choy Katherine K Lloyd Clare M CM Hayday Adrian C AC Noble Alistair A
The Journal of allergy and clinical immunology 20080919 5
<h4>Background</h4>Infection or stimulation of the innate immune system by nonspecific microbial antigens is thought to educate the immune system to respond appropriately to allergens, preventing allergy.<h4>Objective</h4>To determine the immunologic pathways that might explain how infection/microbial exposure inhibits allergic sensitization.<h4>Methods</h4>Immunologic studies of non-antigen-specific functions of CD8 memory cells, their maturation in vivo, and their effects in a mouse asthma mod ...[more]