Ontology highlight
ABSTRACT:
SUBMITTER: Teng M
PROVIDER: S-EPMC3389767 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Teng Mingxiang M Ichikawa Shoji S Padgett Leah R LR Wang Yadong Y Mort Matthew M Cooper David N DN Koller Daniel L DL Foroud Tatiana T Edenberg Howard J HJ Econs Michael J MJ Liu Yunlong Y
Bioinformatics (Oxford, England) 20120518 14
<h4>Motivation</h4>One of the fundamental questions in genetics study is to identify functional DNA variants that are responsible to a disease or phenotype of interest. Results from large-scale genetics studies, such as genome-wide association studies (GWAS), and the availability of high-throughput sequencing technologies provide opportunities in identifying causal variants. Despite the technical advances, informatics methodologies need to be developed to prioritize thousands of variants for pot ...[more]