Ontology highlight
ABSTRACT:
SUBMITTER: Diaz-Albiter H
PROVIDER: S-EPMC3390674 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Diaz-Albiter Hector H Sant'Anna Mauricio R V MR Genta Fernando A FA Dillon Rod J RJ
The Journal of biological chemistry 20120529 28
Phlebotomine sand flies are the vectors of medically important Leishmania. The Leishmania protozoa reside in the sand fly gut, but the nature of the immune response to the presence of Leishmania is unknown. Reactive oxygen species (ROS) are a major component of insect innate immune pathways regulating gut-microbe homeostasis. Here we show that the concentration of ROS increased in sand fly midguts after they fed on the insect pathogen Serratia marcescens but not after feeding on the Leishmania t ...[more]