Ontology highlight
ABSTRACT:
SUBMITTER: Horiguchi K
PROVIDER: S-EPMC3391666 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Horiguchi K K Sakamoto K K Koinuma D D Semba K K Inoue A A Inoue S S Fujii H H Yamaguchi A A Miyazawa K K Miyazono K K Saitoh M M
Oncogene 20111031 26
Epithelial-mesenchymal transition (EMT) is a crucial event in wound healing, tissue repair and cancer progression in adult tissues. We have recently shown that transforming growth factor (TGF)-β-induced EMT involves isoform switching of fibroblast growth factor receptors by alternative splicing. We performed a microarray-based analysis at single exon level to elucidate changes in splicing variants generated during TGF-β-induced EMT, and found that TGF-β induces broad alteration of splicing patte ...[more]