Diagnostic accuracy of spot urinary protein and albumin to creatinine ratios for detection of significant proteinuria or adverse pregnancy outcome in patients with suspected pre-eclampsia: systematic review and meta-analysis.

ABSTRACT:

Objective

To determine the diagnostic accuracy of two "spot urine" tests for significant proteinuria or adverse pregnancy outcome in pregnant women with suspected pre-eclampsia.

Design

Systematic review and meta-analysis.

Data sources

Searches of electronic databases 1980 to January 2011, reference list checking, hand searching of journals, and contact with experts.

Inclusion criteria

Diagnostic studies, in pregnant women with hypertension, that compared the urinary spot protein to creatinine ratio or albumin to creatinine ratio with urinary protein excretion over 24 hours or adverse pregnancy outcome. Study characteristics, design, and methodological and reporting quality were objectively assessed.

Data extraction

Study results relating to diagnostic ac

SUBMITTER: Morris RK 

PROVIDER: S-EPMC3392077 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature